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Although both oxidized and antioxidant levels of lipids are higher in RA-FLS than in healthy controls, the increase in antioxidant levels is slightly higher than that of oxidation, indicating that RA-FLS is resistant to ferroptosis ( + T-cells from ferroptosis ( In studying TNF-, an important inflammatory mediator in the pathogenesis of RA, it was found that small doses of TNF- could enhance Cys uptake and GSH synthesis by activating the NF-B pathway

Although ferroptosis shows great potential in B cell immunomodulation and tumor therapy, the current treatment of DLBCL still faces significant challenges: the sensitivity of the GCB subtype to ferroptosis and the resistance of the ABC subtype create a therapeutic dilemma

Amaranth also functions as a gluten-free pseudocereal, making it an effective gluten-free diet choice

Nature (2017) 541(7635):415

doi: 10.3390/nu8040226 19