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[118] have reported that zinc concentrations are inversely associated with insulin resistance but not correlated with metabolic syndrome

Papilledema Secondary to Neurologic Lyme Borreliosis: A Meta-Case Series

10.1038/s41569-020-00477-1 21

Research indicates that the DHODH pathway can protect cells from oxidative stress and mitochondrial damage through various mechanisms, including downregulating ROS levels, maintaining mitochondrial membrane potential, and inhibiting cell apoptosis (77, 78)

Researchers have firmly linked the use of these drugs to B12 deficiency although that possibility may not outweigh the need for the medication