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Calcium imaging shows that, in all interneurons studied so far, bAPs can propagate and evoke calcium signals in proximal dendrites, and in some types of interneurons reach distal parts of the dendritic tree (Rozsa et al., 2004) or even induce global dendritic calcium spikes, e.g., in LTS cells from L5 of the neocortex (Goldberg et al., 2+ ] i rise mediated by VGCCs can be further amplified by release from internal stores (Topolnik et al., 2009