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Phase 2 trials demonstrated 10.612.8% mean body weight reduction with tesofensine at 24 weeks, whereas 5-Amino-1MQ lacks large-scale human clinical validation beyond preclinical models

A minimalist and robust chemo-photothermal nanoplatform capable of augmenting autophagy-modulated immune response against breast cancer

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IL-1, IL-6 and TNF-) were decreased in mouse lungs after clodronate treatment (Additional file 1: Figure S2)

Bouligny IM, Montalban-Bravo G, Sasaki K, Daver N, Jabbour E, Alvarado Y, DiNardo CD, Ravandi F, Borthakur G, Bose P, Pemmaraju N , Kornblau S, Kadia T, Masarova L, Takahashi K, Andreeff M, Bazinet A, Yang H, Kanagal-Shamanna R, Hosing C, Pierce S, Meyer M, Huang X, Garcia-Manero G

Antioxidant and bioenergetic coupling between neurons and astrocytes