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474 Genitourinary dysfunction Genitourinary dysfunction in DAN encompasses both bladder dysfunction (diabetic cystopathy) and sexual dysfunction

In mature astrocytes differentiated from human induced pluripotent stem cells (iPSC)-derived astrocyte progenitors, ketamine can exert rapid antidepressant effects through the activation of amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) glutamate receptors, and estrogen enhances this effect of ketamine by increasing the gene expression of AMPA receptor subunits

Data analysis Microsoft Excel 2016 software was used to collate data

Ho TC, LaMere MW, Kawano H, Byun DK, LaMere EA, Chiu YC, Chen C, Wang LJ, Wang J, Ramdas B, Dokholyan NV, Calvi LM, Liesveld JL, Jordan CT, Singh RK, Kapur R, Becker MW Leukemia

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Gastroenterology [Internet]