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PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 35 H 48 N 10 O 15 Weight: 848.81 g/mol CAS: 62568-57-4 Structure: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu PHYSICAL PROPERTIES Form: White lyophilized powder Solubility: Water-soluble BBB Penetration: Crosses blood-brain barrier Storage: Keep refrigerated 3646 F (28 C)

Compound Performance Two EGFR inhibitors Generation 1, Gefitinib, and Generation 3, Osimertinib were tested in our model and analyzed through LCMS/MS

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The mechanism is multifactorial: fibroblast activation, matrix-protein modulation, and inflammatory damping

Often, yes