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Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, et al

By delineating the relationship between the key inflammatory mediator GSDMD in SCs and oxidative damage in HCs, we defined an underlying intercellular signaling circuit in NIHL

doi: 10.1016/S2213-2600(21)00435-5 69 WilliamsDMLeeGRCartwrightGE

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There is accumulating evidence for diverse changes in molecular expression of reactive astrocytes in different types and different severities of tissue pathology, 62,65,68,69 but there is not yet a good synthesis of how molecular, metabolic, 87 structural, and functional changes relate to one another to generate precisely definable phenotypes