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Since idiopathic vitiligo is considered an acquired syndrome, the relevance of the genetic contribution should be taken into account even though the disease is not necessarily inherited by the offspring (Karelson et al

PTGS-1 (COX-1) is constitutively expressed in many different cell types and is responsible for the formation of prostaglandins, regulating a large number of physiological processes such as gastroprotection (Langenbach et al

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A total of 45 mice were divided into four groups: UV (n = 15), UV + PDT (n = 10), UV + NAC (n = 10), and UV + NAC + PDT (n = 10)

For instance, selectively targeting the NMT1-NAC interaction surface or the NMT1 ribosomal anchor might impair myristoylation of a subset of proteins with less systemic toxicity than broad active-site inhibitors

Peptides change that equation