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For this purpose, activation of adaptive stress responses was investigated for DNA damage (p21), oxidative stress (SRXN1), inflammation (ICAMI), and ER stress (CHOP) using a HepG2-based GFP-reporter assay (Wink et al., 2014, 2017)

BBA-Gen Subjects 1830:33043316 Gogos A, Shapiro L (2002) Large conformational changes in the catalytic cycle of glutathione synthase

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This last point is speculative

Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimers disease-related blood brain barrier dysfunction and inflammation

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