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Personality traits: Individuals with low self-esteem, a pessimistic outlook, or who are highly self-critical may be more prone to developing depression

Inter-tissue and Inter-species Characteristics of the Mitochondrial Carnitine Palmitoyltransferase Enzyme System

By proposing mitochondria as a potential player, this review provides a fresh framework for investigating hEDS, shifting the focus from solely ECM abnormalities to include cellular energetics and mitochondrial dynamics

doi: 10.1126/sciadv.1500472

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It is associated with microbial translocation from the gut into the interstitium and perivascular tissues resulting in systemic inflammation, abnormalities of lipid and glucose metabolism, atherosclerosis, and hypertension