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Five glutathione S-transferase gene variants in 23,452 cases of lung cancer and 30,397 controls: meta-analysis of 130 studies

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A pathway analysis of how those specific miRNAs interact shows that they affect cytokine signaling, mTOR, and the immune response to microbial infections.[ref] To add a little more complexity here, miRNAs are affected by SNPs in their DNA as well as SNPs in the mRNAs that they bind to

While ferroptosis remains the most iron-dependent form of cell death and displays the most pronounced amplification of lipid peroxidation, recent studies demonstrate that disturbances in iron homeostasis can also influence pyroptosis and necroptosis (Du et al., 2024)