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2.11 Limited proteolysis Limited proteolysis involves controlled digestion of a protein with a protease under specific conditions to see which parts of a protein are flexible or exposed and therefore more accessible to protease, and which are protected and rigid

doi:10.1111/head.14901 Haseeb ME, Mohammed HE, Yaser H, et al

When 100 mg/kg body weight curcumin is administered orally or intraperitoneally, a plasma concentration of 1,250 ng/ml is reached after 30 min (510 times greater than when curcumin is administered alone), and this concentration lasts for 12 h [423]