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In this review, we summarize the regulation of the System X c /GSH/GPX4 axis, a major antioxidant system in ferroptosis, and its potential role in drug-resistant solid tumors therapy, and also conclude with a summary of drugs, compounds and nanoparticles targeting this axis that have been studied in recent years

Sulfur amino acid and Se contents of the diet regulate tissue GSH concentration [79]

Glutathione was administered orally or transdermally to children aged 3 to 13 during an eight-week clinical study

& Tsakiridis, T

Some observations on the effect of folic acid antagonists on acute leukemia and other forms of incurable cancer

Par ailleurs, la molcule protge les cellules contre les radicaux libres