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Disclosures: Pedro Ochoa-Allemant: Nothing to Disclose, Rebecca Hubbard: Nothing to Disclose, David Kaplan: AstraZeneca Inc: Grant/Research Support, Roche Genentech: Independent Contractor, Exact Sciences: Grant/Research Support, Glycotest: Grant/Research Support, Sirtex: Advisor, Exelixis: Advisor, AstraZeneca: Advisor, Marina Serper: Transplant Genomics: Grant/Research Support, Grifols: Grant/Research Support, Eurofins: Grant/Research Support 1066 ANALYSIS OF THE DISTRIBUTION AND SEVERITY OF LIVER FIBROSIS STAGES AMONG THE LOCAL POPULATION WITHIN THE RIO GRANDE VALLEY: IDENTIFICATION OF RISK FACTORS AND ACCURACY OF NON-INVASIVE DIAGNOSTIC TOOLS Dimple Desai Rashmee Patil 1 , 1 South Texas Research Institute Background: In the Rio Grande Valley of South Texas, a region with a high prevalence of metabolic disorders such as diabetes, obesity, and hypertension, liver fibrosis presents as a significant health challenge in the Hispanic population

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On the other hand, the novel oral iron chelator CN128 has shown superior iron chelation and antioxidant properties in clinical trials (148)

Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex

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doi: 10.1074/jbc.274.30.20796 87 ManabeSWadaO