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Conclusions These findings indicate that an EGCGZnbased thermosensitive rectal suppository is a safe and effective localized strategy for alleviating radiation-induced proctitis, with potential translational value for the management of radiation-associated rectal injury

Lifelong overexpression of NAMPT can maintain NAD + content and functionality in the skeletal muscle of aged mice (Frederick et al., 2016)

When this regulatory mechanism is impaired, SQOR accumulates abnormally, leading to a sharp decrease in testicular H 2 S and severe oxidative stress (elevated ROS levels and diminished antioxidants like glutathione and SOD)

The mobile phase comprised of (A) 10 mM ammonium formate in 60% aqueous acetonitrile containing 0.1% formic acid and (B) 10 mM ammonium formate in 9:1 mixture of isopropanol and acetonitrile with a 0.5 mL/min flow rate maintained during a 20 min run

K.HeroldF.LanghansC.HeinrichsK.et al (2025)

Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways