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In rodent models, daily treatment with honey Aloe vera formulation (670 L/kg) profoundly diminished Ki-67 expression in tumor tissues, suggesting cell cycle arrest ( 4.2 Apoptosis induction pathways Apoptosis, a type of controlled cell death required for tissue balance and removal of irregular cells, is commonly defective in cancers ( Table 3 )

202,203,204 AXIN is a scaffold protein of the degradation complex, and mutation of AXIN1/2 substantially affects Wnt signal transduction activity

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The physicians interpretation confirms the deficiency

Mol Aspects Med 30 , 1-12 (2009)

C., & Billewicz, W