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Biochemistry (Mosc.) 2000;65:856861

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10.1073/pnas.1106750109 51 GohG

acyl type protecting groups for example, formyl, trifluoroacetyl, acetyl aromatic urethane type protecting groups for example benzyloxycarboyl (Cbz) and substituted Cbz aliphatic urethane protecting groups for example, t-butyloxycarbonyl (Boc the side chain protecting group remains intact during coupling and is not split off during the deprotection of the amino-terminus protecting group or during coupling

Abstract Purpose To elucidate mechanisms of renal excretion of pudexacianinium (ASP5354) and evaluate renal impairment effects on pharmacokinetics, safety, and tolerability of pudexacianinium