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Safety Considerations and Who Should Monitor More Closely Women with polycystic ovary syndrome (PCOS), endometriosis, or dysmenorrhea already experience dysregulated hormonal cycles and heightened GI sensitivity

Low levels can contribute to brain fog, irritability, and even mild depression

IGF-1's metabolic effects extend to whole-body energy balance through its regulation of growth hormone secretion

"Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model." Circulation

Previous studies have consistently reported a direct positive correlation between HOMA-IR and oxidative stress 35,48

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