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The suppressed activity of GPx8 has been shown to inhibit the development of renal cell tumors by modulating nicotinamide N-methyltransferase (NNMT) (Nguyen et al

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Accordingly, we are finalizing a revision to the definition of an opioid use disorder treatment service at 410.67(b) by adding paragraph (x) to account for these type of coordinated care and/or referral services, provided by an OTP to link a beneficiary with community resources to address unmet health-related social needs or the need and interest for harm reduction interventions and recovery support services that significantly limit the ability to diagnose or treat a patient's opioid use disorder. We are also revising 410.67(d)(4)(i) by adding paragraph (G) to specify that for the coordinated care and/or referral services described in paragraph (x) of the definition of OUD treatment service at 410.67(b), an adjustment will be made when each additional 30 minutes of these services are furnished, to the bundled payment