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Almost three quarters of the CD8+ T cells from this patient were TEMRAs, which are senescent T cells with poor proliferative potential associated with poor survival in cancer patients ( Figure 4 A gradual re-emergence of TEM and proportionate reduction of TEMRA was evident at tp1 and tp2 ( Figure 4A
Nutrient-dependent mTORC1 association with the ULK1Atg13FIP200 complex required for autophagy
These range from visual stimulation experiments that allow us to tap into the specific sets of retinal ganglion cells that are most vulnerable early in the disease, to the evolution of new imaging techniques, largely thanks to Alf Dubra and Vivek Srinivasans work in those areas, and the ability to image retinal ganglion cells and their component parts like their axons which degenerate very early in glaucoma