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Epitalons chronic UV benefit is primarily through nocturnal melatonin restoration (pineal aMT6s urinary ELISA confirming melatonin output, which protects against chronic photodamage via overnight circadian antioxidant surge)

Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Institutional and/or National Research Committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards

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PLoS One 11 , e0149296 (2016)