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76 KawadaH.SawanoboriM.Tsuma-KanekoM.WasadaI.MiyamotoM.MurayamaH.et al (2014)

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For the survival experiment, mice were checked daily and were culled when they showed visible distress symptoms such as weight loss of 10% or more, ascites equivalent to full-term pregnancy, reduced or slow activity, pale feet, hunching, piloerection, closed eyes and isolation from cage mates

Slow replication fork velocity of homologous Recombination-Defective cells results from endogenous oxidative stress