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Metabolic adaptation and maladaptation in adipose tissue

Many of these enzymes have been shown to promote lung tumour growth by a variety of mechanisms, including enhanced cellular proliferation and increased angiogenesis, which permits endovascular invasion

aquatica DA 1877, E

Ollenschlager, G., et al

Gastroenterology 124 , 14881499 (2003)

Moreover, MG derivative MG-H1 down-regulates PD-L1 expression in tumor cells in metastatic prostate cancer (mPCa), whereas high expression of GLO1 limits the accumulation of MG-H1 and maintains the expression of PD-L1, which inhibits CD8 T cell function and promotes immune escape in mPCa