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Cell-derived soluble oligomers of human amyloid-beta peptides disturb cellular homeostasis and induce apoptosis in primary hippocampal neurons

25 As the first enzyme in the transsulfuration pathway, CBS has a SAM regulatory site and mutation at this site results in homocystinuria, 30 which is closely associated with cancer

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The effluent was alternatively connected to an ESI-triple quadrupole-linear ion trap (QTRAP)-MS