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Trends Cancer 3 (4), 294301

Poly IC triggers a cathepsin D- and IPS-1-dependent pathway to enhance cytokine production and mediate dendritic cell necroptosis

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Results: HCC cells, PLC/PRF/5, and Huh7 showed a marked increase of HIF1a protein with no significant change in the growth curve through 96 hours of culture in hypoxia