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Both compounds demonstrated 811% mean body weight reduction in Phase 2 trials, but cagrilintide operates via appetite suppression while tesofensine acts centrally on neurotransmitter systems

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Pep-21 treatment specifically silenced target miR-21 in B16 melanoma cells and M2 macrophages, reducing tumor cell migration and inhibiting tumor progression

It proves its efficiency in vitro against the oxidative stress induced by H 2 O 2 and ultraviolet radiation on human keratinocytes and neonatal dermal fibroblasts (Yoo et al., 2014)

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Over 68 weeks, the semaglutide arm achieved a mean weight loss of 14,9% compared to 2,4% for placebo