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The 1.53 M concentrations of SERF2 that allow phase separation in the presence of rG4s are below the SERF2 concentrations present in human cells which range from ~7 M in U2OS cells to ~23 M in MCF7 breast cancer cells 61

However, composite fillings are a safer and more biocompatible alternative for many patients, especially those concerned about amalgam fillings side effects

The limit of detection was defined as 3 standard deviations for the field blank samples as described in 4

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