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Kaempferol Targeting on the Fibroblast Growth Factor Receptor 3-ribosomal S6 Kinase 2 Signaling axis Prevents the Development of Rheumatoid Arthritis

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Accumulating evidence further demonstrates that in pSS models, reduced gut microbiome diversity and diminished production of microbiota-derived metabolites lead to decreased tolerogenic dendritic cells (DCs) and Th17/Treg imbalance, consequently promoting autoantibody accumulation and exacerbation of glandular inflammatory responses in pSS (203)

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10.19723/j.issn.1671-167X.2022.03.003 110 LeeE.Sidoryk-WegrzynowiczM.YinZ.WebbA.SonD