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Formononetin, an isoflavone, not only inhibits degranulation of mast cells and basophils but also directly suppresses IgE production by human peripheral blood mononuclear cells through modulation of the JAK/STAT/PI3K-Akt signaling pathway, thereby attenuating allergic responses (127)

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2006 Oct;46(10):1163-70

[4] This carrier protein transports B12 to tissues throughout the body, including the liver (where significant stores accumulate), bone marrow, and nervous system