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Although three subtypes are essentially characterized by each subtypes predominant features, given the affected vessel system, they may share the common clinical manifestations related to the three typical major organs with the largest surface area of capillaries such as the kidneys, lungs, and skin (Kronbichler et al., 2024)

A40 and A42 are two main forms of A peptide, the longer A42 has a much stronger tendency to oligomerize and aggregate than the shorter A40, and exhibits more neurotoxic effect

doi: 10.1080/2162402X.2018.1494108 Summary Keywords SLC7A11 (xCT), metabolism, cysteine (Cys), gastrointestinal tract, ferroptosis, oxidative stress, Cancer therapy Citation Jyotsana N, Ta KT and DelGiorno KE (2022) The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer

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Intl Rev Cytol 1978;54:109-157

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