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Arginine metabolic regulators such as spermidine have been shown to suppress M1 macrophage-associated cytokines while inducing M2 macrophage-related markers, significantly alleviating EAE symptoms, whereas Arg1 inhibitors can reverse these effects (96)

3096510-51-6 Molecular Weight 749.77 Formula C 41 H 35 N 9 O 6 SMILES O=C(NC1=C(C#N)C(C2=CC=C(C)C=C2)=C(C#N)C3=NC4=CC=CC=C4N13)CC(NCCCCCNC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)=O Shipping Room temperature in continental US

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We also found that SSO significantly inhibited cell death following PA treatment in SUM-159 and MCF-7 cells, confirming the involvement of CD36 in PA-induced apoptosis and ferroptosis in our models

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