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Our results prompt further studies to better understand the molecular mechanisms responsible for the different and complex effects of Cd on the intestinal cells, which may accumulate and trap high levels of Cd under some nutritional conditions (Eklund et al

In IBD therapy, these include thiopurines, methotrexate, ciclosporin and biologic or targeted cell therapies[41]

We systematically examine the role of ferroptosis in five specific skin diseases, including ichthyosis, psoriasis, polymorphous light eruption (PMLE), vitiligo, and melanoma, detailing its influence on disease pathogenesis and progression

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One double insertion mutant was also analyzed