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Overall, we evaluate whether these disease-modifying emerging therapeutics hold promise as interventions that may be able to reverse or halt AD progression

For example, ROS produced by neutrophils or tumour cells can be transferred to T cells and cause OS, thereby causing hyporeactivity of T cells in cancer patients (185)

Saha Turna N, Comstock SS, Gangur V, Wu F (2023) Effects of aflatoxin on the immune system: Evidence from human and mammalian animal research

Membrane disruption and lipid peroxidation: the cell membrane is a primary target

For example, mutant p53 can induce noncanonical NFB (NCNFB) signaling through the cGASSTING pathway, which promotes tumor cell invasion, metastasis, and immunosuppression

[DOI] [PMC free article] [PubMed] [Google Scholar] 833.Wu Q, et al