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Glutathione peroxidases (GPXs) are an enzyme family with peroxidase activity that protects organisms from oxidative damage by reducing lipid hydroperoxides and free hydrogen peroxide 5

The occurrence of diarrhea was defined as the maintenance of a fecal score at 2 or 3 for 2 consecutive days

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Discussion In this study, a systematic review was first conducted as a hypothesis-driven approach to objectively evaluate the main pathological changes during OA development and identify potential therapeutic targets