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Invest Ophthalmol Vis Sci 36(12):25502555 Sai Varsha MK, Raman T, Manikandan R (2014) Inhibition of diabetic-cataract by vitamin K1 involves modulation of hyperglycemia-induced alterations to lens calcium homeostasis

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For comparison, a multi-dose treatment with Nrf2 activators such as isothiocyanate-containing broccoli seeds, sulforaphane, erucin, or else the potent sulforaphane analog 6-methylsulfinylhexyl isothiocyanate, was needed to achieve similar levels of induction in the cytosolic fraction of liver in adult mice, i.e