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Though this study was not without its flaws, it nonetheless inspired further studies to verify its findings, including a similar 2020 study

Research indicates that acute viral infections, such as SARS-CoV-2, can directly infect mast cells or trigger them via widespread inflammatory signaling, leaving them in a chronically hyper-reactive state

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Its stimulating effects are comparable, although encouraged rather than forced

10.1104/pp.109.136630 Plant Physiol

Factors such as age, underlying health conditions, and the presence of other antioxidants in the body can significantly impact the efficacy of melatonin