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6b) While this would impair killing of VSMC and VEC, which could help prevent ASCVD progression, it would similarly prevent CD8 + T cells from suppressing inflammatory CD4 + T cells, APCs that promote immune activation, and plasma cells that produce inflammatory IgG 2,4

Psoriasis has been associated with keratinocyte production of LL-37 antimicrobial peptide able to trigger the release of pro-inflammatory cytokines and sustaining proliferation [47]

In addition, nutrients can act as signaling molecules involved in lung colonization

Di Magno L, Di Pastena F, Bordone R, Coni S, Canettieri G

Data availability The datasets generated and analysed during the current study are available included in this article and its supplemental information files