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For example, targeting TXNIP can suppress NLRP3 inflammasome activation, offering a promising anti-inflammatory strategy (184)

It is characterized by rapid neuronal death and extracellular matrix degradation post-injury, culminating in cavity formation and long-term neurological deficits (217, 218)

Due to the complexity of the kidney, as an organ containing specialized structures and multiple cell types, it becomes quite difficult to find a reliable model system to study the effects or toxicity of drugs and their metabolites on this organ

Many people dont get enough vitamin C through their diet, leaving their immune system and energy levels weaker than they should be

The top 5 enriched pathways of the PLS2 + genes were Translation, Metabolism of RNA, plasma membrane bounded cell projection assembly, Neddylation, and SUMO is transferred from E1 to E2 (UBE2I, UBC9)

Tau protein hypothesis Besides the A protein deposition, hyperphosphorylated or abnormally phosphorylated Tau protein aggregated into neuronal neurofibrillary tangles is also one of the primary pathogeneses of AD [35,36,37]