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In Parkinsons disease models, riboflavin activates the Nrf2/HO-1 pathway, mitigating mitochondrial complex I-mediated ROS overproduction and safeguarding dopaminergic neurons (e.g., substantia nigra) (10, 64)

Based on this systematic review of the literature, this article summarizes current advances in the modulation of inflammationoxidative stress networks by natural products and elucidates their compoundtargetpathway interactions, thus providing theoretical foundations and innovative therapeutic perspectives for the treatment of viral pneumonia (Table 1

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doi: 10.1186/1471-2431-14-78 52 HosseiniEShahhoseiniMAfsharianPKarimianLAshrafiMMehraeinFet al

Watson CJ, Whitledge JD, Siani AM, Burns MM