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Description

AMG-458 is a potent inhibitor of the c-Met, VEGFR-2, and IGFR1 receptor signaling pathways, inhibitor with radiosensitizing effects

FDA press announcement (2025) 11

However, currently, there are no HGF inhibitors that have been tried in lymphoma treatment, so here, we will focus on c-MET inhibitors, their application in lymphoma treatment (Table 2)