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Table 4 includes a summary of ADCs anti-HER3, anti-MET, anti-CEACAM5, and anti-I6 in NSCLC

The overexpression of Sirt1 has been reported to reduce S aggregation and promote the survival of dopaminergic neuronal cells (Guo et al., 2016), while a small molecule Sirt1 agonist has been found to protect neurons from cell death in a PD animal model ((Lofrumento et al., 2014)