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Common adverse effects include gastrointestinal symptoms (nausea, diarrhea, constipation), which typically improve with continued use

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This dynamic approach allows research teams to promptly respond to any safety issues that may emerge, whether through dose adjustments, enhanced participant supervision, or temporary cessation of treatment

In contrast, ChiA did not affect C9 polymerization (Fig

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Proposed Mechanism of Action In theory, the vaccine works by: Delivering mRNA instructions encoding tumour-related antigens Presenting these antigens to immune cells Activating cytotoxic T-cells Directing immune attack toward cancer cells Despite these theoretical mechanisms, several key questions remain unanswered: Which tumour antigens are targeted Which cancer types are included Whether immune activation leads to real tumour shrinkage How long the immune response lasts What side effects may occur