hforms of glutathione Treatments 101: Part 1 — The Mother All Antioxidants Glutathione Reduced Glutathione Gsh Endogenous

doi: 10.1038/s41575-020-0269-9 13 ZhouZSunBYuDZhuC

2 Molecular mechanisms of ferroptosis In 2003, the Stockwell Lab identified a non-apoptotic form of cell death when they used the small molecule erastin to stimulate the oncogenic RAS-mutant human cancer cell line while screening anticancer drug libraries (Yang and Stockwell, 2008)

Figure S3 In-hospital mortality

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Therefore, the newly synthesized NRF2 accumulates in the cell, enabling it to exert its antioxidant and cellular protective functions [26]