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This reduces reactive tension and helps prevent skin from darkening with tone issues

An in vitro study carried out on a vincristine-resistant human colorectal carcinoma cell line had demonstrated that curcumin was not only toxic to the cancer cells in a dose-dependent manner, as the concentration started to rise from 25 M onwards, but also could reverse their sensitivity to drugs such as fluorouracil, vincristine, hydroxycamptothecin, and cisplatin [241]

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All authors contributed to manuscript revision, read, and approved the submitted version

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These actions play a crucial role in maintaining immune homeostasis and preventing excessive inflammation, which can damage tissues and organs