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Increased expression of the ectoenzyme CD38 in peripheral blood plasmablasts and plasma cells of patients with systemic sclerosis

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While both forms support B12 levels, hydroxocobalamin provides a more sustained effect, making it suitable for treating deficiencies and urgent medical conditions

However, the absence of human clinical trials means the safety profile in humans is entirely unknown

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MRM multiple reaction monitoring the 1-MNA NNMT reaction product was quantified from peak area ratios using AB Sciex Analyst and MultiQuant 2.1 software and the parent precursor and Q3 masses set to m/z 137.1 and 94.1, respectively