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Depletion of beneficial taxa such as Odoribacter (Bacteroidetes) and Lachno Clostridium (Firmicutes), along with increased abundance of pro-inflammatory taxa including Ileibacterium and Olsenella , was associated with reduced SCFA gene expression, downregulation of tight junction proteins (occludin and claudin-1), and microglial activation in the amygdala and arcuate nucleus, indicating gut barrier disruption and neuroinflammation that coincided with anxiety-like behavior

The body can make glycine on its own or you can get it through foods like dairy, meat, fish, and legumes

(Berlin: Springer), 127

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The long-term effects of GLP1s are still being studied, and it is unclear whether patients will need to stay on the medication forever or if they can eventually stop taking it without gaining weight back 8m0s

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