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Upon binding, IGF-1R undergoes autophosphorylation, recruiting insulin receptor substrate (IRS) proteins and Shc adaptor molecules

Reduce smoking, caffeine, and alcohol intake

S-Acetyl L-Glutathione is an altered form with an attached acetyl function group

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J Biol Chem 271:97549758 Mandal PK, Shukla D (2020) KALPANA: advanced spectroscopic signal processing platform for improved accuracy to aid in early diagnosis of brain disorders in clinical setting

Diminished growth and enhanced glucose metabolism in triple Knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5