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Compared with EtOH-fed WT mice, KO mice were less susceptible to EtOH-induced deleterious effects, including body weight loss (reflected by less body weight gain), liver weight gain and hepatocyte damage (reflected by plasma ALT activity) (Table 1)

Institutional Requirements Academic and commercial research facilities maintain strict protocols

For instance, HSD suppressed tumor growth and lung metastasis in a murine model of breast cancer, possibly by inducing hyperosmotic stress or through mimicking CR