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Joo Pessoa Univ

In ligature induced experimental periodontitis, the increase in vascular permeability in the gingival tissue proximal to the ligature is proportional to the extent of local inflammation

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Ethics declarations All the experiments were performed as per the ethical guidelines on animal experimentations provided by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), GOI, New Delhi

It is highly appreciated for its excellent tonic and invigorating action

Patients with severe disease (MDF score of 32, with or without hepatic encephalopathy) and lacking contraindications to steroid use should be considered for a four week course of prednisolone (40 mg/day for 28 days, typically followed by discontinuation or a 2-week taper) (Class I, level A)