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classified as a compounded drug with active import alerts Human trial evidence / Zero completed Phase II or III RCTs in any condition as of 2025 Tumor-promotion signal / Rat models show accelerated solid-tumor growth at supraphysiologic doses Cardiovascular concern / Dual vasomotor activity reported: hypotension at low doses, hypertension at high doses in rodents Hormonal interference / Modulates dopamine and serotonin pathways

GHK-Cu is a naturally occurring copper-binding tripeptide that your body produces and uses as a repair signal

Avoid both injectable and topical use in these populations without clinician oversight

doi: 10.1136/openhrt-2019-001011

Well as we have been using tranexamic acid to treat these patients since the 1980s, several of them also suffered from melasma, and reported this happy side effect of a clearer complexion